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Rang. Pharmacology. 8e. 2015.

0. Contents
Section 1: General principles
1. What is pharmacology?
2. How drugs act: general principles
3. How drugs act: molecular aspects
4. How drugs act: cellular aspects-excitation, contraction and secretion
5. How drugs act: biopharmaceuticals & gene therapy
6. Cell proliferation, apoptosis, repair and regeneration
7. Cellular mechanisms: host defence
8. Method and measurement in pharmacology
9. Drug absorption and distribution
10. Drug metabolism and elimination
11. Pharmacokinetics
12. Individual Variation Pharmacogenetics, pharmacogenomics and ‘personalised medicine’
Section 2: Chemical mediators
13. Chemical mediators and the autonomic nervous system
14. Cholinergic transmission
15. Noradrenergic transmission
16. 5-Hydroxytryptamine and the pharmacology of migraine
17. Purines
18. Local hormones : Histamine & biologically active lipids peptides
19. Local hormones : Peptides & proteins
20. Cannabinoids
21. Nitric oxide & related mediators
Section 3: Drugs affecting major organ systems
22. The heart
23. The vascular system
24. Atherosclerosis and lipoprotein metabolism
25. Haemostasis and thrombosis
26. Haemopoietic system and treatment of anaemia
27. Anti-inflammatory and immunosuppressant drugs
28. Skin
29. The respiratory system

28. The kidney
29. The gastrointestinal tract
30. The control of blood glucose and drug treatment of diabetes mellitus
31. Obesity
32. The pituitary and the adrenal cortex
33. The thyroid
34. The reproductive system
35. Bone metabolism
Section 4: The nervous system
36. Chemical transmission and drug action in the central nervous system
37. Amino acid transmitters
38. Other transmitters and modulators
39. Neurodegenerative diseases
40. General anaesthetic agents
41. Analgesic drugs
42. Local anaesthetics and other drugs affecting sodium channels
43. Anxiolytic and hypnotic drugs
44. Antiepileptic drugs
45. Antipsychotic drugs
46. Antidepressant drugs
47. CNS stimulants and psychotomimetic drugs
48. Drug addiction, dependence and abuse
Section 5: Drugs used for the treatment of infections, cancer and immunological disorders
49. Basic principles of antimicrobial chemotherapy
50. Antibacterial drugs
51. Antiviral drugs
52. Antifungal drugs
53. Antiprotozoal drugs
54. Anthelminthic drugs
55. Anticancer drugs
Section 6: Special topics
56. Individual variation and drug interaction
57. Harmful effects of drugs
58. Lifestyle drugs and drugs in sport
59. Biopharmaceuticals and gene therapy
60. Drug discovery and development